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News and Perspectives
Update on HER2 Positive Breast Cancer (Dr. Eric Winer, July 2009)
Approximately 20 percent of women with breast cancer have what is called HER2 positive disease. In these tumors, there are extra copies of the HER2 gene in the nucleus of the cancer cell and, as a result, excess HER2 protein on the surface of the cancer cell. The HER2 proteins on the surface of the cancer cell interact with each other and with other proteins, and when these interactions occur, they cause the cancer cell to behave in a more aggressive manner.
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PARP Inhibitors (Dr. Eric Winer, June 2009)
I am headed back to Boston after this year’s American Society of Clinical Oncology (ASCO) meeting in Orlando, and I want to share the results of two important studies that are likely to change breast cancer treatment in the years ahead. Both of these studies are preliminary, and neither will change treatment approaches for many months to come, but the findings of each were very promising.
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Triple Negative Breast Cancer (Dr. Eric Winer, February 2009)
When Nancy Block-Zenna was diagnosed in 2005 with the rare and aggressive form of breast cancer known as triple negative breast cancer, two of her friends created the Triple Negative Breast Cancer Foundation (TNBCF) with just $9,000 to raise awareness and funds for the disease. TNBCF is now a major advocacy organization for women with this form of the disease.
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